We have spent 45+ years collecting items from the four evolving companies of J.C. Ayer & Company. This book allows us to document the items collected and the stories related to the company's early growing, mature, and declining years. We document the initial dates of all their products. We track the evolution of their medicinal formulas and the bottles in which the were distributed. We provide extensive images of the company's various advertising formats from quarter sized encased postage to huge railroad billboards and all the trade cards and signs in between. Additionally, we evaluate the medicines provided by the company in light of the state-of-the-art medicines provided by the doctors and druggists of the same period of time.